null
SMILES: Cc1cc(cc2nc(oc12)-c1ccc(cc1)C(=O)N1CCN(CC1)c1ccc(cc1)C(F)(F)F)C#N
InChI Key: InChIKey=LXOWGPYXCUXQFY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50337158 (7-methyl-2-(4-(4-(4-(trifluoromethyl)phenyl)pipera...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of CETP | Bioorg Med Chem Lett 21: 1890-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.090 BindingDB Entry DOI: 10.7270/Q2NG4QW6 | |||||||||||
More data for this Ligand-Target Pair |