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SMILES: COC(CN1CCN(CC1)c1ccc(cc1)C(F)(F)F)Cc1ccc(cc1)-c1nc2cc(cc(C)c2o1)C#N

InChI Key: InChIKey=IHQHQYDJCSAWCM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337162   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50337162
PNG
(2-(4-(2-methoxy-3-(4-(4-(trifluoromethyl)phenyl)pi...)
Show SMILES COC(CN1CCN(CC1)c1ccc(cc1)C(F)(F)F)Cc1ccc(cc1)-c1nc2cc(cc(C)c2o1)C#N
Show InChI InChI=1S/C30H29F3N4O2/c1-20-15-22(18-34)17-27-28(20)39-29(35-27)23-5-3-21(4-6-23)16-26(38-2)19-36-11-13-37(14-12-36)25-9-7-24(8-10-25)30(31,32)33/h3-10,15,17,26H,11-14,16,19H2,1-2H3
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Similars
Article
PubMed
n/an/a 8.94E+3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CETP

Bioorg Med Chem Lett 21: 1890-5 (2011)


Article DOI: 10.1016/j.bmcl.2010.11.090
BindingDB Entry DOI: 10.7270/Q2NG4QW6
More data for this
Ligand-Target Pair