BDBM50337188 4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(5-(4-fluoro-5-isopropyl-2-methoxyphenyl)pyridin-2-yl)piperidin-4-yl)methyl)benzamide::CHEMBL1684865

SMILES: COc1cc(F)c(cc1-c1ccc(nc1)N1CCC(CNC(=O)c2ccc(cc2)-c2nc3cc(cc(C(C)C)c3o2)C#N)CC1)C(C)C

InChI Key: InChIKey=OWJPXIXEZGCOBM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50337188 (4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(...) Show SMILES COc1cc(F)c(cc1-c1ccc(nc1)N1CCC(CNC(=O)c2ccc(cc2)-c2nc3cc(cc(C(C)C)c3o2)C#N)CC1)C(C)C Show InChI InChI=1S/C39H40FN5O3/c1-23(2)30-18-32(35(47-5)19-33(30)40)29-10-11-36(42-22-29)45-14-12-25(13-15-45)21-43-38(46)27-6-8-28(9-7-27)39-44-34-17-26(20-41)16-31(24(3)4)37(34)48-39/h6-11,16-19,22-25H,12-15,21H2,1-5H3,(H,43,46)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem Lett 21: 1890-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.090 BindingDB Entry DOI: 10.7270/Q2NG4QW6
					More data for this Ligand-Target Pair