BDBM50337189 4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(5-(2-isopropoxy-5-methylphenyl)pyridin-2-yl)piperidin-4-yl)methyl)benzamide::CHEMBL1684866

SMILES: CC(C)Oc1ccc(C)cc1-c1ccc(nc1)N1CCC(CNC(=O)c2ccc(cc2)-c2nc3cc(cc(C(C)C)c3o2)C#N)CC1

InChI Key: InChIKey=RFVZHLFBZOOMGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50337189 (4-(5-cyano-7-isopropylbenzo[d]oxazol-2-yl)-N-((1-(...) Show SMILES CC(C)Oc1ccc(C)cc1-c1ccc(nc1)N1CCC(CNC(=O)c2ccc(cc2)-c2nc3cc(cc(C(C)C)c3o2)C#N)CC1 Show InChI InChI=1S/C39H41N5O3/c1-24(2)32-19-28(21-40)20-34-37(32)47-39(43-34)30-9-7-29(8-10-30)38(45)42-22-27-14-16-44(17-15-27)36-13-11-31(23-41-36)33-18-26(5)6-12-35(33)46-25(3)4/h6-13,18-20,23-25,27H,14-17,22H2,1-5H3,(H,42,45)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CETP				Bioorg Med Chem Lett 21: 1890-5 (2011) Article DOI: 10.1016/j.bmcl.2010.11.090 BindingDB Entry DOI: 10.7270/Q2NG4QW6
					More data for this Ligand-Target Pair