BDBM50337330 5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682352::US9163007, 10

SMILES: Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1

InChI Key: InChIKey=GMPRARRULJWWPH-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50337330 (5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...) Show SMILES Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C16H12FN5/c17-14-4-1-11(2-5-14)9-22-10-16(20-21-22)12-3-6-15-13(7-12)8-18-19-15/h1-8,10H,9H2,(H,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	56.3	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc. US Patent					Assay Description 11 data point. Cdc7 kinase assays were carried out in 25 mM HEPES, pH 7.5, 1 mM DTT, 10 mM MgCl2, 100 μM Na3VO4, and 0.075 mg/ml Triton X-100 u...				US Patent US9163007 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DTG
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50337330 (5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...) Show SMILES Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C16H12FN5/c17-14-4-1-11(2-5-14)9-22-10-16(20-21-22)12-3-6-15-13(7-12)8-18-19-15/h1-8,10H,9H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of GSK3-beta after 1 hr				Bioorg Med Chem Lett 21: 1476-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.007 BindingDB Entry DOI: 10.7270/Q2R78FGJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50337330 (5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...) Show SMILES Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C16H12FN5/c17-14-4-1-11(2-5-14)9-22-10-16(20-21-22)12-3-6-15-13(7-12)8-18-19-15/h1-8,10H,9H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrate				Bioorg Med Chem Lett 21: 1476-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.007 BindingDB Entry DOI: 10.7270/Q2R78FGJ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50337330 (5-(1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...) Show SMILES Fc1ccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)cc1 Show InChI InChI=1S/C16H12FN5/c17-14-4-1-11(2-5-14)9-22-10-16(20-21-22)12-3-6-15-13(7-12)8-18-19-15/h1-8,10H,9H2,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.65E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Pim1 after 1 hr using biotinylated AL1peptide as substrate				Bioorg Med Chem Lett 21: 1476-9 (2011) Article DOI: 10.1016/j.bmcl.2011.01.007 BindingDB Entry DOI: 10.7270/Q2R78FGJ
					More data for this Ligand-Target Pair