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SMILES: CN(C)C(=O)CCN1CCN(C[C@@H]2C[C@@]2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=UBLMHOGWPZTKCS-RBISFHTESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337412   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuromedin-K receptor


(Homo sapiens (Human))		BDBM50337412
PNG
((1S,2R)-1-(3,4-dichlorophenyl)-2-((4-(3-(dimethyla...)
Show SMILES CN(C)C(=O)CCN1CCN(C[C@@H]2C[C@@]2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1 |r|
Show InChI InChI=1S/C28H35Cl2FN4O2/c1-32(2)26(36)10-11-34-12-14-35(15-13-34)19-22-17-28(22,21-6-9-24(29)25(30)16-21)27(37)33(3)18-20-4-7-23(31)8-5-20/h4-9,16,22H,10-15,17-19H2,1-3H3/t22-,28+/m0/s1
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Similars
Article
PubMed
 17n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells

Bioorg Med Chem Lett 21: 1498-501 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.135
BindingDB Entry DOI: 10.7270/Q23J3D8R
More data for this
Ligand-Target Pair