BDBM50337428 CHEMBL1682631::rac-2-((4-acetamido-4-phenylpiperidin-1-yl)methyl)-N-(3-chlorobenzyl)-1-(3,4-dichlorophenyl)-N-methylcyclopropanecarboxamide

SMILES: CN(Cc1cccc(Cl)c1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=NUISDCKIKSBXQV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50337428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50337428 (CHEMBL1682631 | rac-2-((4-acetamido-4-phenylpiperi...) Show SMILES CN(Cc1cccc(Cl)c1)C(=O)C1(CC1CN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C32H34Cl3N3O2/c1-22(39)36-31(24-8-4-3-5-9-24)13-15-38(16-14-31)21-26-19-32(26,25-11-12-28(34)29(35)18-25)30(40)37(2)20-23-7-6-10-27(33)17-23/h3-12,17-18,26H,13-16,19-21H2,1-2H3,(H,36,39)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells				Bioorg Med Chem Lett 21: 1498-501 (2011) Article DOI: 10.1016/j.bmcl.2010.12.135 BindingDB Entry DOI: 10.7270/Q23J3D8R
					More data for this Ligand-Target Pair