null
SMILES: CC(N)C1(CCCCC1)c1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=CELRKOSFIVSEBS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]serotonin reuptake at human recombinant SERT expressed in LLC-PK1 cells by liquid scintillation counting | Bioorg Med Chem Lett 21: 1434-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.019 BindingDB Entry DOI: 10.7270/Q2CV4J2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]norepinephrine reuptake at human human recombinant NET expressed in HEK293 cells by scintillation counting | Bioorg Med Chem Lett 21: 1434-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.019 BindingDB Entry DOI: 10.7270/Q2CV4J2P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 527 | n/a | n/a | n/a | n/a | n/a | n/a |
SUNOVION PHARAMCEUTICALS INC. US Patent | Assay Description Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c... | US Patent US10562878 (2020) BindingDB Entry DOI: 10.7270/Q2XP77BX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
SUNOVION PHARAMCEUTICALS INC. US Patent | Assay Description Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ... | US Patent US10562878 (2020) BindingDB Entry DOI: 10.7270/Q2XP77BX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuroepithelial cell-transforming gene 1 protein (Homo sapiens) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SUNOVION PHARAMCEUTICALS INC. US Patent | Assay Description Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293... | US Patent US10562878 (2020) BindingDB Entry DOI: 10.7270/Q2XP77BX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50337908 (1-(1-(biphenyl-4-yl)cyclohexyl)ethanamine | CHEMBL...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine reuptake at human human recombinant DAT expressed in COS-7 cells by scintillation counting | Bioorg Med Chem Lett 21: 1434-7 (2011) Article DOI: 10.1016/j.bmcl.2011.01.019 BindingDB Entry DOI: 10.7270/Q2CV4J2P | |||||||||||
More data for this Ligand-Target Pair |