BDBM50338026 (S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)pyrrolidin-1-yl)-3-(4-(pyrazin-2-yl)piperidin-1-yl)propan-1-one::CHEMBL1684294

SMILES: Clc1cc2nc([nH]c2cc1Cl)[C@@H]1CCCN1C(=O)CCN1CCC(CC1)c1cnccn1

InChI Key: InChIKey=LUYSYRSQNLCVNS-NRFANRHFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysosomal Pro-X carboxypeptidase (Mus musculus)	BDBM50338026 ((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...) Show SMILES Clc1cc2nc([nH]c2cc1Cl)[C@@H]1CCCN1C(=O)CCN1CCC(CC1)c1cnccn1 |r| Show InChI InChI=1S/C23H26Cl2N6O/c24-16-12-18-19(13-17(16)25)29-23(28-18)21-2-1-8-31(21)22(32)5-11-30-9-3-15(4-10-30)20-14-26-6-7-27-20/h6-7,12-15,21H,1-5,8-11H2,(H,28,29)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PrCP in mouse plasma assessed as angiotensin 3 cleavage				Bioorg Med Chem Lett 21: 1299-305 (2011) Article DOI: 10.1016/j.bmcl.2011.01.090 BindingDB Entry DOI: 10.7270/Q2VX0GSS
					More data for this Ligand-Target Pair
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50338026 ((S)-1-(2-(5,6-dichloro-1H-benzo[d]imidazol-2-yl)py...) Show SMILES Clc1cc2nc([nH]c2cc1Cl)[C@@H]1CCCN1C(=O)CCN1CCC(CC1)c1cnccn1 |r| Show InChI InChI=1S/C23H26Cl2N6O/c24-16-12-18-19(13-17(16)25)29-23(28-18)21-2-1-8-31(21)22(32)5-11-30-9-3-15(4-10-30)20-14-26-6-7-27-20/h6-7,12-15,21H,1-5,8-11H2,(H,28,29)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human PrCP				Bioorg Med Chem Lett 21: 1299-305 (2011) Article DOI: 10.1016/j.bmcl.2011.01.090 BindingDB Entry DOI: 10.7270/Q2VX0GSS
					More data for this Ligand-Target Pair