BDBM50338065 3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-yl)-N,N-dimethylprop-2-yn-1-amine::CHEMBL1684667

SMILES: CN(C)CC#Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12

InChI Key: InChIKey=CATNPGATOOPPKF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50338065 (3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-y...) Show SMILES CN(C)CC#Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12 Show InChI InChI=1S/C19H17N5/c1-24(2)10-4-5-13-7-8-14-12-17(21-16(14)11-13)19-18-15(22-23-19)6-3-9-20-18/h3,6-9,11-12,21H,10H2,1-2H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Nycomed GmbH Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay				Bioorg Med Chem Lett 21: 1852-6 (2011) Article DOI: 10.1016/j.bmcl.2011.01.035 BindingDB Entry DOI: 10.7270/Q2MC90BW
					More data for this Ligand-Target Pair