BDBM50338215 1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)-2-chlorophenyl)-3-(5-methylisoxazol-3-yl)urea::CHEMBL1681945

SMILES: CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2cc(C)on2)c(Cl)c1

InChI Key: InChIKey=JAYHAMUXZLQMEL-QPJQQBGISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338215 (1-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CO\N=C\c1c(N)ncnc1Oc1ccc(NC(=O)Nc2cc(C)on2)c(Cl)c1 Show InChI InChI=1S/C17H16ClN7O4/c1-9-5-14(25-29-9)24-17(26)23-13-4-3-10(6-12(13)18)28-16-11(7-22-27-2)15(19)20-8-21-16/h3-8H,1-2H3,(H2,19,20,21)(H2,23,24,25,26)/b22-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair