BDBM50338230 2-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yloxy)phenyl)-N-methylacetamide::CHEMBL1681960

SMILES: CNC(=O)Cc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1

InChI Key: InChIKey=RLQVHFOMIXBRDW-DNTJNYDQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50338230 (2-(4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-...) Show SMILES CNC(=O)Cc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1 Show InChI InChI=1S/C15H17N5O3/c1-17-13(21)7-10-3-5-11(6-4-10)23-15-12(8-20-22-2)14(16)18-9-19-15/h3-6,8-9H,7H2,1-2H3,(H,17,21)(H2,16,18,19)/b20-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 21: 1815-8 (2011) Article DOI: 10.1016/j.bmcl.2011.01.053 BindingDB Entry DOI: 10.7270/Q2ZP46DK
					More data for this Ligand-Target Pair