BDBM50338242 6-propyl-2-ureido-5,6-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide::CHEMBL1681969

SMILES: CCCn1ncc-2c1CCc1c-2sc(NC(N)=O)c1C(N)=O

InChI Key: InChIKey=HDTRRKOWUKWYQX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50338242 (6-propyl-2-ureido-5,6-dihydro-4H-thieno[2,3-e]inda...) Show SMILES CCCn1ncc-2c1CCc1c-2sc(NC(N)=O)c1C(N)=O Show InChI InChI=1S/C14H17N5O2S/c1-2-5-19-9-4-3-7-10(12(15)20)13(18-14(16)21)22-11(7)8(9)6-17-19/h6H,2-5H2,1H3,(H2,15,20)(H3,16,18,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyorin Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human IKK-beta by substrate phosphorylation assay				Bioorg Med Chem Lett 21: 1758-62 (2011) Article DOI: 10.1016/j.bmcl.2011.01.069 BindingDB Entry DOI: 10.7270/Q2TX3FPV
					More data for this Ligand-Target Pair