BDBM50338368 3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)quinoline-4-carboxamide::CHEMBL1682938

SMILES: CC[C@H](NC(=O)c1c(c(nc2ccccc12)-c1ccccc1)S(C)=O)c1ccccc1

InChI Key: InChIKey=BQWCXAMITVBWIR-FEAGIOCNSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50338368 (3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)...) Show SMILES CC[C@H](NC(=O)c1c(c(nc2ccccc12)-c1ccccc1)S(C)=O)c1ccccc1 |r| Show InChI InChI=1S/C26H24N2O2S/c1-3-21(18-12-6-4-7-13-18)28-26(29)23-20-16-10-11-17-22(20)27-24(25(23)31(2)30)19-14-8-5-9-15-19/h4-17,21H,3H2,1-2H3,(H,28,29)/t21-,31?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human NK3 receptor expressed in CHO cells assessed as inhibition of senktide-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 21: 1896-9 (2011) Article DOI: 10.1016/j.bmcl.2010.11.003 BindingDB Entry DOI: 10.7270/Q2XP7586
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50338368 (3-(methylsulfinyl)-2-phenyl-N-((S)-1-phenylpropyl)...) Show SMILES CC[C@H](NC(=O)c1c(c(nc2ccccc12)-c1ccccc1)S(C)=O)c1ccccc1 |r| Show InChI InChI=1S/C26H24N2O2S/c1-3-21(18-12-6-4-7-13-18)28-26(29)23-20-16-10-11-17-22(20)27-24(25(23)31(2)30)19-14-8-5-9-15-19/h4-17,21H,3H2,1-2H3,(H,28,29)/t21-,31?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human NK3 receptor expressed in CHO cells assessed as inhibition of senktide-induced calcium flux by FLIPR assay				Bioorg Med Chem Lett 21: 1896-9 (2011) Article DOI: 10.1016/j.bmcl.2010.11.003 BindingDB Entry DOI: 10.7270/Q2XP7586
					More data for this Ligand-Target Pair