BDBM50338505 (3'S,4'S)-4'-amino-1'-(6-(2,4,5-trifluorophenyl)pyrimidin-4-yl)-1,3'-bipyrrolidin-2-one::CHEMBL1683558

SMILES: N[C@H]1CN(C[C@@H]1N1CCCC1=O)c1cc(ncn1)-c1cc(F)c(F)cc1F

InChI Key: InChIKey=AHMISODBMDDBSB-HOCLYGCPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338505 ((3'S,4'S)-4'-amino-1'-(6-(2,4,5-trifluorophenyl)py...) Show SMILES N[C@H]1CN(C[C@@H]1N1CCCC1=O)c1cc(ncn1)-c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C18H18F3N5O/c19-11-5-13(21)12(20)4-10(11)15-6-17(24-9-23-15)25-7-14(22)16(8-25)26-3-1-2-18(26)27/h4-6,9,14,16H,1-3,7-8,22H2/t14-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	488	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 21: 1810-4 (2011) Article DOI: 10.1016/j.bmcl.2011.01.055 BindingDB Entry DOI: 10.7270/Q28W3DM7
					More data for this Ligand-Target Pair