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SMILES: CC(=O)NCCNC(=O)c1cn(Cc2ccc(F)c(c2)C(F)(F)F)cn1

InChI Key: InChIKey=JFAARJDEYWKLQP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338530   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Rattus norvegicus (Rat))		BDBM50338530
PNG
(CHEMBL1683585 | N-(2-acetamidoethyl)-1-(4-fluoro-3...)
Show SMILES CC(=O)NCCNC(=O)c1cn(Cc2ccc(F)c(c2)C(F)(F)F)cn1
Show InChI InChI=1S/C16H16F4N4O2/c1-10(25)21-4-5-22-15(26)14-8-24(9-23-14)7-11-2-3-13(17)12(6-11)16(18,19)20/h2-3,6,8-9H,4-5,7H2,1H3,(H,21,25)(H,22,26)
PDB

UniProtKB/SwissProt

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PC sid
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Article
PubMed
n/an/a 2.75E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of rat liver SCD1 using [3H]-stearoylCoA

Bioorg Med Chem Lett 21: 1621-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.113
BindingDB Entry DOI: 10.7270/Q2571C9J
More data for this
Ligand-Target Pair