BDBM50338623 (R)-3-amino-1-(3-(4-(carboxyl)phenyl)-6,7-dihydro-[1,2,3]triazolo[1,5-a]pyrazin-5(4H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride::CHEMBL1683992

SMILES: N[C@@H](CC(=O)N1CCn2nnc(c2C1)-c1ccc(cc1)C(O)=O)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=AKGVZAMLOAMAEF-OAHLLOKOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50338623 ((R)-3-amino-1-(3-(4-(carboxyl)phenyl)-6,7-dihydro-...) Show SMILES N[C@@H](CC(=O)N1CCn2nnc(c2C1)-c1ccc(cc1)C(O)=O)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C22H20F3N5O3/c23-16-10-18(25)17(24)8-14(16)7-15(26)9-20(31)29-5-6-30-19(11-29)21(27-28-30)12-1-3-13(4-2-12)22(32)33/h1-4,8,10,15H,5-7,9,11,26H2,(H,32,33)/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33.8	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University of Traditional Chinese Medicine Curated by ChEMBL					Assay Description Inhibition of human DPP4 assessed as hydrolytic reaction of Ala-Pro-AMC				Bioorg Med Chem Lett 21: 1731-5 (2011) Article DOI: 10.1016/j.bmcl.2011.01.086 BindingDB Entry DOI: 10.7270/Q2N58MN7
					More data for this Ligand-Target Pair