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SMILES: COc1cccc2CC(COc12)c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1

InChI Key: InChIKey=KAULBGZYEKPLDK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM50338697
PNG
(2-(8-methoxychroman-3-yl)-6-(1H-pyrazol-4-yl)quina...)
Show SMILES COc1cccc2CC(COc12)c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1
Show InChI InChI=1S/C21H18N4O3/c1-27-18-4-2-3-13-7-14(11-28-19(13)18)20-24-17-6-5-12(15-9-22-23-10-15)8-16(17)21(26)25-20/h2-6,8-10,14H,7,11H2,1H3,(H,22,23)(H,24,25,26)
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UniChem

Similars
Article
PubMed
n/an/a 423n/an/an/an/an/an/a



Translational Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 by HTRF assay

Bioorg Med Chem Lett 21: 1844-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.039
BindingDB Entry DOI: 10.7270/Q20G3KFF
More data for this
Ligand-Target Pair