BDBM50339012 7-chlorothieno[3,2-b]pyridin-5(4H)-one::CHEMBL1688209

SMILES: Clc1cc(=O)[nH]c2ccsc12

InChI Key: InChIKey=MDEADSGMJSCOBN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3-phosphoinositide dependent protein kinase-1 (Homo sapiens (Human))	BDBM50339012 (7-chlorothieno[3,2-b]pyridin-5(4H)-one | CHEMBL168...) Show SMILES Clc1cc(=O)[nH]c2ccsc12 Show InChI InChI=1S/C7H4ClNOS/c8-4-3-6(10)9-5-1-2-11-7(4)5/h1-3H,(H,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximi...				ACS Med Chem Lett 1: 439-442 (2010) Article DOI: 10.1021/ml100136n BindingDB Entry DOI: 10.7270/Q22807WJ
					More data for this Ligand-Target Pair