BindingDB logo
myBDB logout

null

SMILES: [O-][N+](=O)c1ccccc1N1CCN(CC1)C(=O)COCc1ccccc1

InChI Key: InChIKey=DMNVIYPPINZEFA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339070   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50339070
PNG
(2-(benzyloxy)-1-(4-(2-nitrophenyl)piperazin-1-yl)e...)
Show SMILES [O-][N+](=O)c1ccccc1N1CCN(CC1)C(=O)COCc1ccccc1
Show InChI InChI=1S/C19H21N3O4/c23-19(15-26-14-16-6-2-1-3-7-16)21-12-10-20(11-13-21)17-8-4-5-9-18(17)22(24)25/h1-9H,10-15H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.80E+3n/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Positive allosteric modulation at rat mGluR5 receptor expressed in HEK293 cells assessed as glutamate-induced calcium fluorescence by Fluo-4/AM dye-b...

ACS Med Chem Lett 1: 433-438 (2010)


Article DOI: 10.1021/ml100181a
BindingDB Entry DOI: 10.7270/Q2DJ5FX7
More data for this
Ligand-Target Pair