BDBM50339082 6-[(3-Cyclopropylmethoxy-4-isopropylphenyl)-ethylamino]nicotinic acid::CHEMBL1688384

SMILES: CCN(c1ccc(C(C)C)c(OCC2CC2)c1)c1ccc(cn1)C(O)=O

InChI Key: InChIKey=HXRVJXWCLPGNFN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50339082 (6-[(3-Cyclopropylmethoxy-4-isopropylphenyl)-ethyla...) Show SMILES CCN(c1ccc(C(C)C)c(OCC2CC2)c1)c1ccc(cn1)C(O)=O Show InChI InChI=1S/C21H26N2O3/c1-4-23(20-10-7-16(12-22-20)21(24)25)17-8-9-18(14(2)3)19(11-17)26-13-15-5-6-15/h7-12,14-15H,4-6,13H2,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at RXRalpha transfected in human COS1 cells after 18 hrs by luciferase reporter gene transactivation assay				ACS Med Chem Lett 1: 521-525 (2010) Article DOI: 10.1021/ml100184k BindingDB Entry DOI: 10.7270/Q28S4Q6X
					More data for this Ligand-Target Pair