BDBM50339196 CHEMBL1689465

SMILES: CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C)C(C)C)[C@@H](C)O

InChI Key: InChIKey=QZBYJBLPYNMHBH-DRRMWKONSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339196   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Placenta growth factor (Homo sapiens (Human))	BDBM50339196 (CHEMBL1689465) Show SMILES CC(C)C[C@@H]1NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C1=O)C(=O)N[C@@H](CCCCNC(C)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NC(=O)COCC(=O)Nc1ccc(CCC(=O)N2CCC2=O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C)C(C)C)[C@@H](C)O |r| Show InChI InChI=1S/C102H144N24O26S2/c1-53(2)40-74-102(151)125-38-21-28-77(125)97(146)116-71(43-64-47-105-52-108-64)91(140)118-75(95(144)111-68(27-18-20-37-106-58(10)128)89(138)121-84(54(3)4)98(147)112-67(26-17-19-36-103)88(137)120-80(132)49-152-48-79(131)110-63-32-29-60(30-33-63)31-34-81(133)126-39-35-82(126)134)50-153-154-51-76(119-99(148)85(55(5)6)122-94(143)73(45-83(135)136)115-90(139)69(109-59(11)129)41-61-22-13-12-14-23-61)96(145)114-72(44-78(104)130)92(141)113-70(42-62-46-107-66-25-16-15-24-65(62)66)93(142)123-86(56(7)8)100(149)124-87(57(9)127)101(150)117-74/h12-16,22-25,29-30,32-33,46-47,52-57,67-77,84-87,107,127H,17-21,26-28,31,34-45,48-51,103H2,1-11H3,(H2,104,130)(H,105,108)(H,106,128)(H,109,129)(H,110,131)(H,111,144)(H,112,147)(H,113,141)(H,114,145)(H,115,139)(H,116,146)(H,117,150)(H,118,140)(H,119,148)(H,121,138)(H,122,143)(H,123,142)(H,124,149)(H,135,136)(H,120,132,137)/t57-,67+,68+,69+,70+,71+,72+,73+,74+,75+,76+,77+,84+,85+,86+,87+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Binding affinity to human PlGF-1				J Med Chem 54: 1256-65 (2011) Article DOI: 10.1021/jm101226k BindingDB Entry DOI: 10.7270/Q2BK1CN1
					More data for this Ligand-Target Pair