null

SMILES: CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C

InChI Key: InChIKey=GXWIPZUWQQNHGA-BMHTYJBBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Placenta growth factor (Mus musculus)	BDBM50339213 (CHEMBL1689478) Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC1=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(C)C |r,wU:20.21,8.8,39.41,4.3,64.68,49.56,2.2,124.138,96.100,78.82,111.117,wD:56.60,79.85,85.89,115.126,35.79,30.113,(24.33,-18.35,;22.99,-19.12,;21.66,-18.36,;21.65,-16.82,;20.32,-19.14,;16.38,-21.41,;15.04,-20.63,;13.7,-21.38,;15.06,-19.1,;16.39,-18.34,;16.41,-16.8,;17.75,-16.06,;17.77,-14.52,;16.44,-13.74,;16.47,-12.19,;15.1,-14.49,;15.09,-16.03,;13.73,-18.3,;12.4,-19.06,;12.38,-20.6,;11.05,-18.27,;11.07,-16.73,;9.75,-15.94,;9.61,-14.42,;8.11,-14.08,;7.32,-15.4,;8.33,-16.56,;9.72,-19.05,;9.77,-20.53,;11.12,-21.27,;8.41,-21.3,;8.4,-22.85,;9.74,-23.65,;9.73,-25.22,;11.04,-26.05,;11.04,-27.59,;12.37,-28.37,;12.37,-29.91,;11.03,-30.67,;13.69,-30.67,;13.69,-32.23,;12.34,-32.99,;10.94,-32.36,;9.91,-33.51,;10.67,-34.84,;12.18,-34.53,;15.03,-29.92,;16.35,-30.69,;16.34,-32.23,;17.7,-29.93,;19.15,-30.41,;20.06,-29.17,;19.16,-27.92,;17.7,-28.39,;16.36,-27.64,;15.04,-28.4,;16.36,-26.1,;15.02,-25.33,;13.69,-26.11,;12.35,-25.35,;13.69,-27.65,;17.7,-25.31,;17.68,-23.78,;16.34,-23.02,;19.01,-23,;20.34,-23.77,;20.33,-25.31,;21.66,-26.09,;23,-25.32,;24.33,-26.1,;25.66,-25.33,;24.32,-27.63,;19.04,-21.44,;20.33,-20.69,;21.67,-21.45,;9.7,-28.36,;9.7,-29.89,;8.38,-27.59,;7.05,-28.36,;7.05,-29.9,;5.71,-30.67,;8.38,-30.66,;5.71,-27.58,;5.71,-26.04,;4.37,-28.36,;3.04,-27.58,;3.03,-26.04,;1.69,-25.27,;.37,-26.05,;-.96,-25.28,;-2.3,-26.05,;-3.63,-25.28,;-2.3,-27.59,;1.69,-28.36,;.36,-27.6,;1.7,-29.9,;.38,-30.67,;.38,-32.23,;-.96,-33.01,;-2.31,-32.24,;-3.66,-33.02,;-3.65,-34.58,;-5,-35.37,;-2.29,-35.35,;-.95,-34.57,;-.96,-29.9,;-2.3,-30.68,;-.96,-28.37,;7.09,-20.53,;5.74,-21.28,;5.74,-22.82,;4.4,-20.52,;3.05,-21.29,;1.74,-20.53,;1.73,-19,;.38,-21.31,;.4,-22.84,;-.92,-23.63,;-2.27,-22.88,;-3.58,-23.66,;-2.28,-21.34,;-.92,-20.54,;-.92,-19.01,;.42,-18.24,;-2.25,-18.23,;-2.24,-16.69,;-.9,-15.93,;.42,-16.71,;1.75,-15.94,;1.77,-14.4,;.43,-13.63,;-.9,-14.39,;-3.58,-18.99,;-4.93,-18.21,;-6.29,-18.99,;-4.93,-16.66,;4.39,-18.99,;3.05,-18.21,;5.72,-18.21,)| Show InChI InChI=1S/C90H130N26O21S2/c1-9-48(6)72-86(135)104-59(19-14-32-99-90(94)95)76(125)110-66(34-46(2)3)88(137)116-33-15-20-69(116)84(133)109-65(39-55-41-97-45-101-55)80(129)111-68(83(132)115-73(49(7)117)87(136)105-58(18-13-31-98-89(92)93)75(124)106-61(74(91)123)35-52-21-25-56(119)26-22-52)43-139-138-42-67(82(131)108-64(38-54-40-96-44-100-54)79(128)107-63(81(130)114-72)37-53-23-27-57(120)28-24-53)112-85(134)71(47(4)5)113-77(126)60(29-30-70(121)122)103-78(127)62(102-50(8)118)36-51-16-11-10-12-17-51/h10-12,16-17,21-28,40-41,44-49,58-69,71-73,117,119-120H,9,13-15,18-20,29-39,42-43H2,1-8H3,(H2,91,123)(H,96,100)(H,97,101)(H,102,118)(H,103,127)(H,104,135)(H,105,136)(H,106,124)(H,107,128)(H,108,131)(H,109,133)(H,110,125)(H,111,129)(H,112,134)(H,113,126)(H,114,130)(H,115,132)(H,121,122)(H4,92,93,98)(H4,94,95,99)/t48-,49+,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,71-,72-,73-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse PlGF-VEGFR-1 interaction by ELISA				J Med Chem 54: 1256-65 (2011) Article DOI: 10.1021/jm101226k BindingDB Entry DOI: 10.7270/Q2BK1CN1
					More data for this Ligand-Target Pair