BDBM50339287 3-Phenyl-5-(2,3,4,5-tetrafluorophenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL1689660

SMILES: Fc1cc(-c2cc(=O)n3[nH]c(c(-c4ccccc4)c3n2)C(F)(F)F)c(F)c(F)c1F

InChI Key: InChIKey=LFKRCFSRIIHXRX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50339287 (3-Phenyl-5-(2,3,4,5-tetrafluorophenyl)-2-(trifluor...) Show SMILES Fc1cc(-c2cc(=O)n3[nH]c(c(-c4ccccc4)c3n2)C(F)(F)F)c(F)c(F)c1F Show InChI InChI=1S/C19H8F7N3O/c20-10-6-9(14(21)16(23)15(10)22)11-7-12(30)29-18(27-11)13(8-4-2-1-3-5-8)17(28-29)19(24,25)26/h1-7,28H	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Hebei Medical University Curated by ChEMBL					Assay Description Activation of KCNQ2/Q3 expressed in CHO cells by atomic absorption Rb'+ efflux assay				Eur J Med Chem 46: 934-43 (2011) Article DOI: 10.1016/j.ejmech.2011.01.010 BindingDB Entry DOI: 10.7270/Q2TM7BDF
					More data for this Ligand-Target Pair