BDBM50339321 (5S,7R)-5-phenyl-7-(trifluoromethyl)-N-(4-(trifluoromethyl)benzyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide::CHEMBL1688101

SMILES: FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NCc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key: InChIKey=SMDFTUTXLCAQBO-ZWKOTPCHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339321   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50339321 ((5S,7R)-5-phenyl-7-(trifluoromethyl)-N-(4-(trifluo...) Show SMILES FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NCc1ccc(cc1)C(F)(F)F)c1ccccc1 |r| Show InChI InChI=1S/C22H18F6N4O/c23-21(24,25)15-8-6-13(7-9-15)11-29-20(33)16-12-30-32-18(22(26,27)28)10-17(31-19(16)32)14-4-2-1-3-5-14/h1-9,12,17-18,31H,10-11H2,(H,29,33)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of CaSR expressed in CHO cells incubated with compound for 10 mins measured after 1 hr by [35S]GTPgammaS binding assay				J Med Chem 54: 1430-40 (2011) Article DOI: 10.1021/jm101452x BindingDB Entry DOI: 10.7270/Q2K35TZ9
					More data for this Ligand-Target Pair