BindingDB logo
myBDB logout

null

SMILES: CN(C(=O)N(C)c1cccc(Cl)c1)C(=O)c1ccc2OCOc2c1

InChI Key: InChIKey=MOSCZDBBLMLSFK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339634   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 2


(Homo sapiens (Human))		BDBM50339634
PNG
(1-(Benzo[d][1,3]dioxole-6-carbonyl)-3-(3-chlorophe...)
Show SMILES CN(C(=O)N(C)c1cccc(Cl)c1)C(=O)c1ccc2OCOc2c1
Show InChI InChI=1S/C17H15ClN2O4/c1-19(13-5-3-4-12(18)9-13)17(22)20(2)16(21)11-6-7-14-15(8-11)24-10-23-14/h3-9H,10H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Telik, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of CCL2-induced chemotaxis

J Med Chem 54: 1667-81 (2011)


Article DOI: 10.1021/jm1012903
BindingDB Entry DOI: 10.7270/Q28K79DQ
More data for this
Ligand-Target Pair