null

SMILES: CC[C@H]1CN(Cc2cc(Cl)ccc2OCC(O)=O)CCN1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=RYDKHFBYSXPMIC-SFHVURJKSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50339756 ((S)-2-(4-chloro-2-((3-ethyl-4-(phenylsulfonyl)pipe...) Show SMILES CC[C@H]1CN(Cc2cc(Cl)ccc2OCC(O)=O)CCN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C21H25ClN2O5S/c1-2-18-14-23(10-11-24(18)30(27,28)19-6-4-3-5-7-19)13-16-12-17(22)8-9-20(16)29-15-21(25)26/h3-9,12,18H,2,10-11,13-15H2,1H3,(H,25,26)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ flux				J Med Chem 54: 1779-88 (2011) Article DOI: 10.1021/jm1014549 BindingDB Entry DOI: 10.7270/Q2H41RQJ
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50339756 ((S)-2-(4-chloro-2-((3-ethyl-4-(phenylsulfonyl)pipe...) Show SMILES CC[C@H]1CN(Cc2cc(Cl)ccc2OCC(O)=O)CCN1S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C21H25ClN2O5S/c1-2-18-14-23(10-11-24(18)30(27,28)19-6-4-3-5-7-19)13-16-12-17(22)8-9-20(16)29-15-21(25)26/h3-9,12,18H,2,10-11,13-15H2,1H3,(H,25,26)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay				J Med Chem 54: 1779-88 (2011) Article DOI: 10.1021/jm1014549 BindingDB Entry DOI: 10.7270/Q2H41RQJ
					More data for this Ligand-Target Pair