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SMILES: CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(CC1)C(Oc1cccc(Cl)n1)c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=GWAWCEXQGCBEJE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339989   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 5


(Homo sapiens (Human))		BDBM50339989
PNG
(3,5-dichloro-N-(3-(4-((6-chloropyridin-2-yloxy)(4-...)
Show SMILES CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(CC1)C(Oc1cccc(Cl)n1)c1ccc(cc1)S(C)(=O)=O
Show InChI InChI=1S/C28H31Cl3N4O4S/c1-18(10-13-33-28(36)26-22(29)16-32-17-23(26)30)35-14-11-20(12-15-35)27(39-25-5-3-4-24(31)34-25)19-6-8-21(9-7-19)40(2,37)38/h3-9,16-18,20,27H,10-15H2,1-2H3,(H,33,36)
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Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Genzyme Corp.

Curated by ChEMBL


Assay Description
Displacement of [128I]-RANTES from CCR5 expressed in HEK293F cells

Bioorg Med Chem Lett 21: 2450-5 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.058
BindingDB Entry DOI: 10.7270/Q2F76CV3
More data for this
Ligand-Target Pair