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BDBM50340229 4-amino-1-((6-methylpyridin-3-yl)methyl)-6-((tetrahydrofuran-3-yl)methoxy)-1H-imidazo[4,5-c]pyridin-2(3H)-one::CHEMBL1760586

SMILES: Cc1ccc(Cn2c3cc(OCC4CCOC4)nc(N)c3[nH]c2=O)cn1

InChI Key: InChIKey=KVJIOFLUTIQSPP-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340229   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 7


(Homo sapiens (Human))		BDBM50340229
PNG
(4-amino-1-((6-methylpyridin-3-yl)methyl)-6-((tetra...)
Show SMILES Cc1ccc(Cn2c3cc(OCC4CCOC4)nc(N)c3[nH]c2=O)cn1
Show InChI InChI=1S/C18H21N5O3/c1-11-2-3-12(7-20-11)8-23-14-6-15(26-10-13-4-5-25-9-13)21-17(19)16(14)22-18(23)24/h2-3,6-7,13H,4-5,8-10H2,1H3,(H2,19,21)(H,22,24)
PDB

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Article
PubMed
n/an/an/an/a 474n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Agonist activity at Toll-like receptor 7

Bioorg Med Chem Lett 21: 2389-93 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.092
BindingDB Entry DOI: 10.7270/Q2W66M2C
More data for this
Ligand-Target Pair