BDBM50340478 (1S,3aS,3bS,9aR,9bS,11aS)-N,N-diethyl-9a,11a-dimethyl-7-oxo-5-propyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[i]phenanthridine-1-carboxamide::CHEMBL1762035
SMILES: CCCN1C[C@H]2[C@@H]3CC[C@H](C(=O)N(CC)CC)[C@@]3(C)CC[C@@H]2[C@@]2(C)CCC(=O)C=C12
InChI Key: InChIKey=OCZSFVBWWMYLHE-XOZDTIMBSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid 5-alpha-reductase (Homo sapiens (Human)) | BDBM50340478 ((1S,3aS,3bS,9aR,9bS,11aS)-N,N-diethyl-9a,11a-dimet...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Homo sapiens (human) Steroid 5-alpha-reductase type 2 | Citation and Details Article DOI: 10.1007/s00044-012-0006-1 BindingDB Entry DOI: 10.7270/Q29889WK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase (Mycobacterium tuberculosis) | BDBM50340478 ((1S,3aS,3bS,9aR,9bS,11aS)-N,N-diethyl-9a,11a-dimet...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Stony Brook University Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis 3 beta hydroxysteriod dehydrogenase | Bioorg Med Chem Lett 21: 2216-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.004 BindingDB Entry DOI: 10.7270/Q2Z31ZXD | |||||||||||
More data for this Ligand-Target Pair |