BDBM50340591 Acetic acid 5'-acetoxy-4-trifluoromethyl-[1,1';4',1'']terphenyl-2'-yl ester::CHEMBL1762686

SMILES: CC(=O)Oc1cc(c(OC(C)=O)cc1-c1ccccc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=OOIJDWCZNLQEOD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340591   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50340591 (Acetic acid 5'-acetoxy-4-trifluoromethyl-[1,1';4',...) Show SMILES CC(=O)Oc1cc(c(OC(C)=O)cc1-c1ccccc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C23H17F3O4/c1-14(27)29-21-13-20(17-8-10-18(11-9-17)23(24,25)26)22(30-15(2)28)12-19(21)16-6-4-3-5-7-16/h3-13H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Inhibition of human recombinant BACE1 preincubated after 1 hr by fluorescence assay				Bioorg Med Chem Lett 21: 2183-7 (2011) Article DOI: 10.1016/j.bmcl.2011.03.023 BindingDB Entry DOI: 10.7270/Q2JS9QRG
					More data for this Ligand-Target Pair