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SMILES: Cc1ccc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1

InChI Key: InChIKey=ADWCAKSAEQUTHQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340604   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 10


(Homo sapiens (Human))		BDBM50340604
PNG
(7-(6-methylpyridin-3-yl)-N-(4-(3-morpholino-1H-1,2...)
Show SMILES Cc1ccc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)N3CCOCC3)nc2c1
Show InChI InChI=1S/C26H24N8O/c1-18-2-3-20(15-27-18)19-4-5-21-16-28-25(31-24(21)14-19)30-22-6-8-23(9-7-22)34-17-29-26(32-34)33-10-12-35-13-11-33/h2-9,14-17H,10-13H2,1H3,(H,28,30,31)
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Article
PubMed
n/an/a 730n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK3 by HRTF

Bioorg Med Chem Lett 21: 1719-23 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.079
BindingDB Entry DOI: 10.7270/Q2F1901V
More data for this
Ligand-Target Pair