BDBM50340607 7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-(pyridin-2-yl)-1H-1,2,4-triazol-1-yl)phenyl)quinazolin-2-amine::CHEMBL1761562

SMILES: Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)-c3ccccn3)nc2c1

InChI Key: InChIKey=XQHYPIHJXWTXPZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 10 (Homo sapiens (Human))	BDBM50340607 (7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-(pyridin-2-yl...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)-c3ccccn3)nc2c1 Show InChI InChI=1S/C25H19N9/c1-33-15-19(14-29-33)17-5-6-18-13-27-25(31-23(18)12-17)30-20-7-9-21(10-8-20)34-16-28-24(32-34)22-4-2-3-11-26-22/h2-16H,1H3,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK3 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Transcription factor AP-1 (Homo sapiens (Human))	BDBM50340607 (7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-(pyridin-2-yl...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)-c3ccccn3)nc2c1 Show InChI InChI=1S/C25H19N9/c1-33-15-19(14-29-33)17-5-6-18-13-27-25(31-23(18)12-17)30-20-7-9-21(10-8-20)34-16-28-24(32-34)22-4-2-3-11-26-22/h2-16H,1H3,(H,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of c-Jun				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50340607 (7-(1-methyl-1H-pyrazol-4-yl)-N-(4-(3-(pyridin-2-yl...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(Nc3ccc(cc3)-n3cnc(n3)-c3ccccn3)nc2c1 Show InChI InChI=1S/C25H19N9/c1-33-15-19(14-29-33)17-5-6-18-13-27-25(31-23(18)12-17)30-20-7-9-21(10-8-20)34-16-28-24(32-34)22-4-2-3-11-26-22/h2-16H,1H3,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 by HRTF				Bioorg Med Chem Lett 21: 1719-23 (2011) Article DOI: 10.1016/j.bmcl.2011.01.079 BindingDB Entry DOI: 10.7270/Q2F1901V
					More data for this Ligand-Target Pair