null

SMILES: Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCN)cc3)ccc2n1

InChI Key: InChIKey=QAGXUEMUOSEVRU-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50340704 (CHEMBL1760025 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCN)cc3)ccc2n1 Show InChI InChI=1S/C31H37N5O2/c1-22-18-29(33)28-19-25(12-15-30(28)35-22)36-31(37)27-9-5-4-8-24(27)21-38-26-13-10-23(11-14-26)20-34-17-7-3-2-6-16-32/h4-5,8-15,18-19,34H,2-3,6-7,16-17,20-21,32H2,1H3,(H2,33,35)(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human kappa opioid receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50340704 (CHEMBL1760025 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCN)cc3)ccc2n1 Show InChI InChI=1S/C31H37N5O2/c1-22-18-29(33)28-19-25(12-15-30(28)35-22)36-31(37)27-9-5-4-8-24(27)21-38-26-13-10-23(11-14-26)20-34-17-7-3-2-6-16-32/h4-5,8-15,18-19,34H,2-3,6-7,16-17,20-21,32H2,1H3,(H2,33,35)(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50340704 (CHEMBL1760025 | N-(4-amino-2-methylquinolin-6-yl)-...) Show SMILES Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCCCN)cc3)ccc2n1 Show InChI InChI=1S/C31H37N5O2/c1-22-18-29(33)28-19-25(12-15-30(28)35-22)36-31(37)27-9-5-4-8-24(27)21-38-26-13-10-23(11-14-26)20-34-17-7-3-2-6-16-32/h4-5,8-15,18-19,34H,2-3,6-7,16-17,20-21,32H2,1H3,(H2,33,35)(H,36,37)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Superiore di Sanit£ Curated by ChEMBL					Assay Description Displacement of [3H]-naltrindole from human mu opioid receptor expressed in CHO cells after 2 hrs by scintillation counting				Eur J Med Chem 46: 1207-21 (2011) Article DOI: 10.1016/j.ejmech.2011.01.040 BindingDB Entry DOI: 10.7270/Q2NK3FBC
					More data for this Ligand-Target Pair