BDBM50340732 CHEMBL1762572::N-[5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-2-yl]-N,N',N'-trimethylethane-1,2-diamine

SMILES: CN(C)CCN(C)c1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1

InChI Key: InChIKey=XRRDTBCXEAUXRE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50340732 (CHEMBL1762572 | N-[5,7-Dimethyl-3-(phenylsulfonyl)...) Show SMILES CN(C)CCN(C)c1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H25N5O2S/c1-14-13-15(2)24-18(20-14)17(19(21-24)23(5)12-11-22(3)4)27(25,26)16-9-7-6-8-10-16/h6-10,13H,11-12H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	489	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production after 2 ...				Eur J Med Chem 46: 1189-97 (2011) Article DOI: 10.1016/j.ejmech.2011.01.038 BindingDB Entry DOI: 10.7270/Q2HT2PMN
					More data for this Ligand-Target Pair