BDBM50340790 (E)-N-(4-nitrobenzylidene)-2-naphthohydrazide::CHEMBL1760505

SMILES: [O-][N+](=O)c1ccc(\C=N\NC(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=RUQCGNRXDVIDAJ-XDHOZWIPSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340790   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50340790 ((E)-N-(4-nitrobenzylidene)-2-naphthohydrazide | CH...) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=O)c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C18H13N3O3/c22-18(16-8-7-14-3-1-2-4-15(14)11-16)20-19-12-13-5-9-17(10-6-13)21(23)24/h1-12H,(H,20,22)/b19-12+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Inhibition of human recombinant IKK-beta expressed in insect Sf21 cells using phospho-Ulight-IkappaB-alpha as substrate				Eur J Med Chem 46: 1245-53 (2011) Article DOI: 10.1016/j.ejmech.2011.01.045 BindingDB Entry DOI: 10.7270/Q27M08ZV
					More data for this Ligand-Target Pair