BDBM50341027 CHEMBL1762296::N-(4,5-dimethylisoxazol-3-yl)-4-(tetrahydro-2H-pyran-4-carbonyl)-1,4-diazepane-1-carboxamide

SMILES: Cc1onc(NC(=O)N2CCCN(CC2)C(=O)C2CCOCC2)c1C

InChI Key: InChIKey=DCMAMTDVFZUNEW-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50341027 (CHEMBL1762296 | N-(4,5-dimethylisoxazol-3-yl)-4-(t...) Show SMILES Cc1onc(NC(=O)N2CCCN(CC2)C(=O)C2CCOCC2)c1C Show InChI InChI=1S/C17H26N4O4/c1-12-13(2)25-19-15(12)18-17(23)21-7-3-6-20(8-9-21)16(22)14-4-10-24-11-5-14/h14H,3-11H2,1-2H3,(H,18,19,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated cAMP production				Bioorg Med Chem Lett 21: 2011-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.017 BindingDB Entry DOI: 10.7270/Q2KK9C2M
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50341027 (CHEMBL1762296 | N-(4,5-dimethylisoxazol-3-yl)-4-(t...) Show SMILES Cc1onc(NC(=O)N2CCCN(CC2)C(=O)C2CCOCC2)c1C Show InChI InChI=1S/C17H26N4O4/c1-12-13(2)25-19-15(12)18-17(23)21-7-3-6-20(8-9-21)16(22)14-4-10-24-11-5-14/h14H,3-11H2,1-2H3,(H,18,19,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated cAMP production				Bioorg Med Chem Lett 21: 2011-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.017 BindingDB Entry DOI: 10.7270/Q2KK9C2M
					More data for this Ligand-Target Pair