BDBM50341135 CHEMBL1760547::N-p-Coumaroyl serotonin

SMILES: Oc1ccc(\C=C\C(=O)NCCc2c[nH]c3ccc(O)cc23)cc1

InChI Key: InChIKey=WLZPAFGVOWCVMG-FPYGCLRLSA-N

Data: 1 KI  2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL62 (Saccharomyces cerevisiae)	BDBM50341135 (CHEMBL1760547 | N-p-Coumaroyl serotonin) Show SMILES Oc1ccc(\C=C\C(=O)NCCc2c[nH]c3ccc(O)cc23)cc1 Show InChI InChI=1S/C19H18N2O3/c22-15-4-1-13(2-5-15)3-8-19(24)20-10-9-14-12-21-18-7-6-16(23)11-17(14)18/h1-8,11-12,21-23H,9-10H2,(H,20,24)/b8-3+	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	8.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Uncompetitive inhibition of yeast alpha-glucosidase by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1007/s00044-011-9699-9 BindingDB Entry DOI: 10.7270/Q2930X2H
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341135 (CHEMBL1760547 | N-p-Coumaroyl serotonin) Show SMILES Oc1ccc(\C=C\C(=O)NCCc2c[nH]c3ccc(O)cc23)cc1 Show InChI InChI=1S/C19H18N2O3/c22-15-4-1-13(2-5-15)3-8-19(24)20-10-9-14-12-21-18-7-6-16(23)11-17(14)18/h1-8,11-12,21-23H,9-10H2,(H,20,24)/b8-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
National Institute of Pharmaceutical Education and Research (NIPER) Curated by ChEMBL					Assay Description Inhibition of recombinant human MAOB using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme addition and measured a...				Eur J Med Chem 181: (2019) Article DOI: 10.1016/j.ejmech.2019.07.064
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL62 (Saccharomyces cerevisiae)	BDBM50341135 (CHEMBL1760547 | N-p-Coumaroyl serotonin) Show SMILES Oc1ccc(\C=C\C(=O)NCCc2c[nH]c3ccc(O)cc23)cc1 Show InChI InChI=1S/C19H18N2O3/c22-15-4-1-13(2-5-15)3-8-19(24)20-10-9-14-12-21-18-7-6-16(23)11-17(14)18/h1-8,11-12,21-23H,9-10H2,(H,20,24)/b8-3+	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 min before substrate addition and ...				Citation and Details Article DOI: 10.1007/s00044-011-9699-9 BindingDB Entry DOI: 10.7270/Q2930X2H
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50341135 (CHEMBL1760547 | N-p-Coumaroyl serotonin) Show SMILES Oc1ccc(\C=C\C(=O)NCCc2c[nH]c3ccc(O)cc23)cc1 Show InChI InChI=1S/C19H18N2O3/c22-15-4-1-13(2-5-15)3-8-19(24)20-10-9-14-12-21-18-7-6-16(23)11-17(14)18/h1-8,11-12,21-23H,9-10H2,(H,20,24)/b8-3+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kinki University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase after 25 mins by spectrophotometry				Bioorg Med Chem Lett 21: 1983-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.028 BindingDB Entry DOI: 10.7270/Q2T43TCF
					More data for this Ligand-Target Pair