BDBM50341380 CHEMBL4163622

SMILES: [#6]\[#6](-[#6])=[#6](/[#6])-c1ccc(cc1)-c1cnc(-[#6]-[#6]-[#6](-[#8])=O)o1

InChI Key: InChIKey=CUKBEVXJULALEW-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoid X receptor gamma/retinoic acid receptor alpha (Homo sapiens (Human))	BDBM50341380 (CHEMBL4163622) Show SMILES [#6]\[#6](-[#6])=[#6](/[#6])-c1ccc(cc1)-c1cnc(-[#6]-[#6]-[#6](-[#8])=O)o1 Show InChI InChI=1S/C17H19NO3/c1-11(2)12(3)13-4-6-14(7-5-13)15-10-18-16(21-15)8-9-17(19)20/h4-7,10H,8-9H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Transactivation of human Gal4-fused RXRgamma LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assay				J Med Chem 61: 5442-5447 (2018) Article DOI: 10.1021/acs.jmedchem.8b00494 BindingDB Entry DOI: 10.7270/Q2J38W5N
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50341380 (CHEMBL4163622) Show SMILES [#6]\[#6](-[#6])=[#6](/[#6])-c1ccc(cc1)-c1cnc(-[#6]-[#6]-[#6](-[#8])=O)o1 Show InChI InChI=1S/C17H19NO3/c1-11(2)12(3)13-4-6-14(7-5-13)15-10-18-16(21-15)8-9-17(19)20/h4-7,10H,8-9H2,1-3H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assay				J Med Chem 61: 5442-5447 (2018) Article DOI: 10.1021/acs.jmedchem.8b00494 BindingDB Entry DOI: 10.7270/Q2J38W5N
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha/gamma (Homo sapiens (Human))	BDBM50341380 (CHEMBL4163622) Show SMILES [#6]\[#6](-[#6])=[#6](/[#6])-c1ccc(cc1)-c1cnc(-[#6]-[#6]-[#6](-[#8])=O)o1 Show InChI InChI=1S/C17H19NO3/c1-11(2)12(3)13-4-6-14(7-5-13)15-10-18-16(21-15)8-9-17(19)20/h4-7,10H,8-9H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
Swiss Federal Institute of Technology (ETH) Curated by ChEMBL					Assay Description Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assay				J Med Chem 61: 5442-5447 (2018) Article DOI: 10.1021/acs.jmedchem.8b00494 BindingDB Entry DOI: 10.7270/Q2J38W5N
					More data for this Ligand-Target Pair