Found 6 hits for monomerid = 50341393 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrases; II & IX
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 9 after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase V
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 5B after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase V
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 5A after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 9.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50341393
(CHEMBL4165154)Show SMILES [#6]-[#6](-[#6])[Se;v2]c1ccc(cc1)S([#7])(=O)=O Show InChI InChI=1S/C9H13NO2SSe/c1-7(2)14-9-5-3-8(4-6-9)13(10,11)12/h3-7H,1-2H3,(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florence
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 after 15 mins by stopped flow carbon dioxide hydration assay |
ACS Med Chem Lett 9: 462-467 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00076 BindingDB Entry DOI: 10.7270/Q2319ZFQ |
More data for this Ligand-Target Pair | |