null

SMILES: Oc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1

InChI Key: InChIKey=QHOAINDIUONOKC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50341466 (8-(5-Hydroxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-py...) Show SMILES Oc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C16H14N2O2/c19-14-7-13(8-17-9-14)12-5-10-1-2-15(20)18-4-3-11(6-12)16(10)18/h5-9,19H,1-4H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B2 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50341466 (8-(5-Hydroxypyridin-3-yl)-1,2,5,6-tetrahydro-4H-py...) Show SMILES Oc1cncc(c1)-c1cc2CCN3c2c(CCC3=O)c1 Show InChI InChI=1S/C16H14N2O2/c19-14-7-13(8-17-9-14)12-5-10-1-2-15(20)18-4-3-11(6-12)16(10)18/h5-9,19H,1-4H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of human CYP11B1 expressed in hamster V79 MZh cells assessed as conversion of [4-14C]-11-deoxycorticosterone substrate by HPTLC assay				J Med Chem 54: 2307-19 (2011) Article DOI: 10.1021/jm101470k BindingDB Entry DOI: 10.7270/Q2765FM6
					More data for this Ligand-Target Pair