BDBM50341498 CHEMBL1765619::N-(5-(3-Phenylimidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide

SMILES: O=S(=O)(Nc1cncc(c1)-c1ccc2ncc(-c3ccccc3)n2c1)c1ccccc1

InChI Key: InChIKey=CTKAOJMAEUTJDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50341498 (CHEMBL1765619 | N-(5-(3-Phenylimidazo[1,2-a]pyridi...) Show SMILES O=S(=O)(Nc1cncc(c1)-c1ccc2ncc(-c3ccccc3)n2c1)c1ccccc1 Show InChI InChI=1S/C24H18N4O2S/c29-31(30,22-9-5-2-6-10-22)27-21-13-20(14-25-15-21)19-11-12-24-26-16-23(28(24)17-19)18-7-3-1-4-8-18/h1-17,27H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Korea Advanced Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha after 180 mins by luminescent assay				J Med Chem 54: 2455-66 (2011) Article DOI: 10.1021/jm101582z BindingDB Entry DOI: 10.7270/Q2ZP46F1
					More data for this Ligand-Target Pair