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SMILES: Fc1ccc(c(F)c1)S(=O)(=O)Nc1cncc(c1)-c1ccc2ncc(C#N)n2c1

InChI Key: InChIKey=ZWZOBCUCOLFDDH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341504   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))		BDBM50341504
PNG
(CHEMBL1765625 | N-(5-(3-Cyanoimidazo[1,2-a]pyridin...)
Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cncc(c1)-c1ccc2ncc(C#N)n2c1
Show InChI InChI=1S/C19H11F2N5O2S/c20-14-2-3-18(17(21)6-14)29(27,28)25-15-5-13(8-23-9-15)12-1-4-19-24-10-16(7-22)26(19)11-12/h1-6,8-11,25H
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Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Korea Advanced Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of PI3Kalpha after 180 mins by luminescent assay

J Med Chem 54: 2455-66 (2011)


Article DOI: 10.1021/jm101582z
BindingDB Entry DOI: 10.7270/Q2ZP46F1
More data for this
Ligand-Target Pair