BDBM50341560 (R)-7-chloro-3-(3,5-dimethylphenyl)-6-(4-fluorophenyl)-4-(2-(piperidin-2-yl)ethoxy)quinolin-2(1H)-one::CHEMBL1766107
SMILES: Cc1cc(C)cc(c1)-c1c(OCC[C@H]2CCCCN2)c2cc(c(Cl)cc2[nH]c1=O)-c1ccc(F)cc1
InChI Key: InChIKey=HYLHWMBYNMHMIZ-HSZRJFAPSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50341560 ((R)-7-chloro-3-(3,5-dimethylphenyl)-6-(4-fluorophe...) | KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation counting | J Med Chem 54: 2351-8 (2011) Article DOI: 10.1021/jm101501b BindingDB Entry DOI: 10.7270/Q2668DH8 | |||||||||||
More data for this Ligand-Target Pair |