BDBM50341607 1-benzyl-3-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1-yl)urea::CHEMBL1766359

SMILES: O=C(NCc1ccccc1)Nc1nn(-c2ccccc2)c(=O)c2ccccc12

InChI Key: InChIKey=AYERKGWULZQYMW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50341607 (1-benzyl-3-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1...) Show SMILES O=C(NCc1ccccc1)Nc1nn(-c2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C22H18N4O2/c27-21-19-14-8-7-13-18(19)20(25-26(21)17-11-5-2-6-12-17)24-22(28)23-15-16-9-3-1-4-10-16/h1-14H,15H2,(H2,23,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Firenze Curated by ChEMBL					Assay Description Displacement of [125I]AB-MECA from human cloned adenosine A3 receptor expressed in CHO cells				J Med Chem 54: 2102-13 (2011) Article DOI: 10.1021/jm101328n BindingDB Entry DOI: 10.7270/Q2P84C7S
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50341607 (1-benzyl-3-(4-oxo-3-phenyl-3,4-dihydrophthalazin-1...) Show SMILES O=C(NCc1ccccc1)Nc1nn(-c2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C22H18N4O2/c27-21-19-14-8-7-13-18(19)20(25-26(21)17-11-5-2-6-12-17)24-22(28)23-15-16-9-3-1-4-10-16/h1-14H,15H2,(H2,23,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.15	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Firenze Curated by ChEMBL					Assay Description Antagonist activity at human cloned adenosine A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP accumulation after 15 mi...				J Med Chem 54: 2102-13 (2011) Article DOI: 10.1021/jm101328n BindingDB Entry DOI: 10.7270/Q2P84C7S
					More data for this Ligand-Target Pair