BDBM50341663 (E)-3-(3,4-Dihydroxybenzylidene)chroman-4-one::CHEMBL1766558

SMILES: Oc1ccc(\C=C2/COc3ccccc3C2=O)cc1O

InChI Key: InChIKey=FEXFMUQVKJRJMT-YRNVUSSQSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50341663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341663 ((E)-3-(3,4-Dihydroxybenzylidene)chroman-4-one | CH...) Show SMILES Oc1ccc(\C=C2/COc3ccccc3C2=O)cc1O Show InChI InChI=1S/C16H12O4/c17-13-6-5-10(8-14(13)18)7-11-9-20-15-4-2-1-3-12(15)16(11)19/h1-8,17-18H,9H2/b11-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Universita` La Sapienza di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...				J Med Chem 54: 2155-64 (2011) Article DOI: 10.1021/jm1013709 BindingDB Entry DOI: 10.7270/Q2902435
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50341663 ((E)-3-(3,4-Dihydroxybenzylidene)chroman-4-one | CH...) Show SMILES Oc1ccc(\C=C2/COc3ccccc3C2=O)cc1O Show InChI InChI=1S/C16H12O4/c17-13-6-5-10(8-14(13)18)7-11-9-20-15-4-2-1-3-12(15)16(11)19/h1-8,17-18H,9H2/b11-7+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
Konkuk University Curated by ChEMBL					Assay Description Inhibition of MAO-B (unknown origin)				Bioorg Med Chem 21: 7890-7 (2013) Article DOI: 10.1016/j.bmc.2013.10.004 BindingDB Entry DOI: 10.7270/Q29W0JDC
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50341663 ((E)-3-(3,4-Dihydroxybenzylidene)chroman-4-one | CH...) Show SMILES Oc1ccc(\C=C2/COc3ccccc3C2=O)cc1O Show InChI InChI=1S/C16H12O4/c17-13-6-5-10(8-14(13)18)7-11-9-20-15-4-2-1-3-12(15)16(11)19/h1-8,17-18H,9H2/b11-7+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` La Sapienza di Roma Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...				J Med Chem 54: 2155-64 (2011) Article DOI: 10.1021/jm1013709 BindingDB Entry DOI: 10.7270/Q2902435
					More data for this Ligand-Target Pair