BDBM50341701 CHEMBL1766637::rac-1-[2-(tert-Butyldiphenylsilyloxyethylamido)-4-trityloxybutyl]uracil

SMILES: CC(C)(C)[Si](OCCNC(=O)C(CCOC(c1ccccc1)(c1ccccc1)c1ccccc1)Cn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=DCTPWOAYWKVIJD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341701   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Homo sapiens (Human))	BDBM50341701 (CHEMBL1766637 | rac-1-[2-(tert-Butyldiphenylsilylo...) Show SMILES CC(C)(C)[Si](OCCNC(=O)C(CCOC(c1ccccc1)(c1ccccc1)c1ccccc1)Cn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C46H49N3O5Si/c1-45(2,3)55(40-25-15-7-16-26-40,41-27-17-8-18-28-41)54-34-31-47-43(51)36(35-49-32-29-42(50)48-44(49)52)30-33-53-46(37-19-9-4-10-20-37,38-21-11-5-12-22-38)39-23-13-6-14-24-39/h4-29,32,36H,30-31,33-35H2,1-3H3,(H,47,51)(H,48,50,52)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human dUTPase by spectrophotometric analysis				Bioorg Med Chem 19: 2378-91 (2011) Article DOI: 10.1016/j.bmc.2011.02.012 BindingDB Entry DOI: 10.7270/Q21J9B2W
					More data for this Ligand-Target Pair