BDBM50342137 CHEMBL1766013::Methyl syn-3-(1H-1-Imidazolyl)-3-[4-(2-naphthylamino)phenyl]-2-methylpropanoate

SMILES: COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1

InChI Key: InChIKey=UJBIWWFQIGDZPI-UZUQRXQVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50342137 (CHEMBL1766013 | Methyl syn-3-(1H-1-Imidazolyl)-3-[...) Show SMILES COC(=O)[C@H](C)[C@H](c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 |r| Show InChI InChI=1S/C24H23N3O2/c1-17(24(28)29-2)23(27-14-13-25-16-27)19-8-10-21(11-9-19)26-22-12-7-18-5-3-4-6-20(18)15-22/h3-17,23,26H,1-2H3/t17-,23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation counting				J Med Chem 54: 2778-91 (2011) Article DOI: 10.1021/jm101583w BindingDB Entry DOI: 10.7270/Q2TT4R8J
					More data for this Ligand-Target Pair