BDBM50342143 3-Imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-1-ylamino)-phenyl]-propionicAcid Methyl Ester::CHEMBL1766003

SMILES: COC(=O)C(C)(C)C(c1ccc(Nc2cccc3ccccc23)cc1)n1ccnc1

InChI Key: InChIKey=LPYACPINNUETJT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome CYP26A1 (Homo sapiens (Human))	BDBM50342143 (3-Imidazol-1-yl-2,2-dimethyl-3-[4-(naphthalen-1-yl...) Show SMILES COC(=O)C(C)(C)C(c1ccc(Nc2cccc3ccccc23)cc1)n1ccnc1 Show InChI InChI=1S/C25H25N3O2/c1-25(2,24(29)30-3)23(28-16-15-26-17-28)19-11-13-20(14-12-19)27-22-10-6-8-18-7-4-5-9-21(18)22/h4-17,23,27H,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation counting				J Med Chem 54: 2778-91 (2011) Article DOI: 10.1021/jm101583w BindingDB Entry DOI: 10.7270/Q2TT4R8J
					More data for this Ligand-Target Pair