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SMILES: NC(=O)c1ccsc1NC(=O)Cc1ccc2OCOc2c1

InChI Key: InChIKey=DNTZWULJNGOBHG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342303   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 8


(Homo sapiens (Human))		BDBM50342303
PNG
(2-(2-(benzo[d][1,3]dioxol-5-yl)acetamido)thiophene...)
Show SMILES NC(=O)c1ccsc1NC(=O)Cc1ccc2OCOc2c1
Show InChI InChI=1S/C14H12N2O4S/c15-13(18)9-3-4-21-14(9)16-12(17)6-8-1-2-10-11(5-8)20-7-19-10/h1-5H,6-7H2,(H2,15,18)(H,16,17)
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Article
PubMed
n/an/a 1.80E+3n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK1 by TR-FRET assay

Bioorg Med Chem 19: 2582-8 (2011)


Article DOI: 10.1016/j.bmc.2011.03.017
BindingDB Entry DOI: 10.7270/Q2J966PD
More data for this
Ligand-Target Pair